By I. Soussis MD
How successful is intrauterine insemination in infertile women with endometriosis?
Tummon et al. 1997 enrolled 103 infertile couples with endometriosis stage I and II in a prospective randomized study. Of those patients 53 underwent superovulation treatment with gonadotrophins and intrauterine insemination (127 cycles) and the remaining 50 were the control group and were just observed for 184 cycles. The birth rate in the treatment group were 5-6 higher than the controls.
In another study, initially randomized, Nulsen et al. 1993, compared superovulation with gonadotrophins and intrauterine insemination with insemination without superovulation.
The success rate was 5.7 times higher in the superovulation group.
Werbrouck et al. 2006, studied infertile women with endometriosis, who were treated with gonadotrophins and intrauterine insemination within six months from their laparoscopy. They reported pregnancy rates similar to those with unexplained infertility (20% vs 20,5%).